Deep Eutectic Solvent as a Sustainable Medium for C–C Bond Formation Via Multicomponent Radical Conjugate Additions
نویسندگان
چکیده
Deep eutectic solvents (DESs) have been used for the first time as a sustainable medium in radical-mediated molecular organic synthetic protocols. This study reports an efficient protocol C–C bond formation through radical conjugate addition of simple olefins (di- and trisubstituted). An inexpensive abundant iron catalyst [Fe(acac)3] together with nontoxic silane (poly(methylhydrosiloxane) (PMHS)) was employed, using choline chloride/ethylene glycol (1:2) solvent under air mild reaction conditions. Different functional groups were well tolerated, also, could be carried out on gram scale excellent yields.
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ژورنال
عنوان ژورنال: ACS Sustainable Chemistry & Engineering
سال: 2021
ISSN: ['2168-0485']
DOI: https://doi.org/10.1021/acssuschemeng.1c02193